Emre Sofyali MSc
Early Stage Researcher 6
Name: Emre Sofyali
Gender: Male
Country of Birth: Turkey
MSc in: Molecular Biology, Genetics and Biotechnology (Istanbul Technical University, Turkey)
Marie Skłodowska Curie in Cellular/Molecular/Medical Biology at the Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany, in the Division of Molecular Genome Analysis of Prof. Wiemann. The group aims to understand the complex molecular mechanisms that regulate signalling networks controlling cancer development, metastasis, and drug response as prerequisite to advance personalized treatment. Visit http://www.dkfz.de/en/mga to learn more about the group
Project: “Validate epigenetic resistance specific interference in an in vivo mouse model”
Supervisors: PI Prof. Wiemann (DKFZ), EpiPredict co-PI Dr Ruiters (Synvolux)
PhD programme: DKFZ Int. Helmholtz Graduate School for Cancer Research (www.dkfz.de/en/phd-program) and Faculty of Biosciences, University Heidelberg, Germany
Key Objectives & Expected Results
Expected Results
- Insight how epigenetic interference influences endocrine resistance development in vivo (mouse model)
- Validation of the epigenetic interference experiments performed in resistance-induced clones
Host training: Mouse xenografting, tumour monitoring
Planned secondment(s): Synvolux: Protein/DNA delivery (M9), UMCG: Epigenetic interference (M23-25), UvA: Bioinformatics/modelling (M12)
